Publication: Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro
Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro
Date
Date
Date
Citations
Kuzmanov, A., Salemi, S., Schmid, F. A., Burger, I. A., Eberli, D., & Kranzbühler, B. (2023). Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro. International Journal of Molecular Sciences, 24, 12338. https://doi.org/10.3390/ijms241512338
Abstract
Abstract
Abstract
Prostate-specific membrane antigen (PSMA)-based imaging improved the detection of primary, recurrent and metastatic prostate cancer. However, in certain patients, a low PSMA surface expression can be a limitation for this promising diagnostic tool. Pharmacological induction of PSMA might be useful to further improve the detection rate of PSMA-based imaging. To achieve this, we tested dutasteride (Duta)-generally used for treatment of benign prostatic enlargement-and lovastatin (Lova)-a compound used to reduce blood lipid concentration
Additional indexing
Creators (Authors)
- Kuzmanov, Aleksandar
- Salemi, Souzan
- Schmid, Florian A
- Burger, Irene A
- Eberli, Daniel
- Kranzbühler, Benedikt
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Citations
Kuzmanov, A., Salemi, S., Schmid, F. A., Burger, I. A., Eberli, D., & Kranzbühler, B. (2023). Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro. International Journal of Molecular Sciences, 24, 12338. https://doi.org/10.3390/ijms241512338
