Publication: Individuelle Koffeinempfindlichkeit: Implikationen für eine personalisierte Schlafmedizin?
Individuelle Koffeinempfindlichkeit: Implikationen für eine personalisierte Schlafmedizin?
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Landolt, H. P. (2016). Individuelle Koffeinempfindlichkeit: Implikationen für eine personalisierte Schlafmedizin? Praxis, 105, 563–568. https://doi.org/10.1024/1661-8157/a002352
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The prevalence of the insomnia syndrome and the effects of caffeine on sleep are in part genetically determined. Pharmacogenetic studies in humans demonstrate that functional polymorphisms of the genes encoding adenosine A2A receptors and dopamine transporters contribute to individual differences in impaired sleep quality by caffeine. The A2A receptor and dopamine transporter are preferentially expressed in the striatum. Together, these observations suggest that the striatum plays an important role in sleep-wake regulation. Individual
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- Landolt, Hans Peter
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Landolt, H. P. (2016). Individuelle Koffeinempfindlichkeit: Implikationen für eine personalisierte Schlafmedizin? Praxis, 105, 563–568. https://doi.org/10.1024/1661-8157/a002352
