Publication: Animal models in surgical lymphedema research - a systematic review
Animal models in surgical lymphedema research - a systematic review
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Frueh, F. S., Gousopoulos, E., Rezaeian, F., Menger, M. D., Lindenblatt, N., & Giovanoli, P. (2016). Animal models in surgical lymphedema research - a systematic review. Journal of Surgical Research, 200(1), 208–220. https://doi.org/10.1016/j.jss.2015.07.005
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BACKGROUND: Chronic secondary lymphedema is a well-known complication in oncologic surgery. Autologous lymph node transplantation, lymphovenous anastomosis, and other lymphatic surgeries have been developed in the last decades with rising clinical application. Animal models to explore the pathophysiology of lymphedema and microsurgical interventions have reached great popularity, although the induction of stable lymphedema in animals is still challenging. The aim of this review was to systematically assess lymphedema animal models and
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- Frueh, Florian S
- Gousopoulos, Epameinondas
- Rezaeian, Farid
- Menger, Michael D
- Giovanoli, Pietro
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Frueh, F. S., Gousopoulos, E., Rezaeian, F., Menger, M. D., Lindenblatt, N., & Giovanoli, P. (2016). Animal models in surgical lymphedema research - a systematic review. Journal of Surgical Research, 200(1), 208–220. https://doi.org/10.1016/j.jss.2015.07.005