Publication: Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath
Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath
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García-Gómez, D., Gaisl, T., Bregy, L., Martínez-Lozano Sinues, P., Kohler, M., & Zenobi, R. (2016). Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath. Chemical Communications, 52(55), 8526–8528. https://doi.org/10.1039/c6cc03070j
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Many studies and personalized medicine in general require frequent measurements and/or rapid results of biomarker levels. Here we show that 20 low volatility metabolites of the tryptophan pathway can be detected in exhaled human breath. This real-time and non-invasive method offers an attractive alternative to blood analysis.
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- García-Gómez, Diego
- Gaisl, Thomas
- Bregy, Lukas
- Martínez-Lozano Sinues, Pablo
- Kohler, Malcolm
- Zenobi, Renato
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García-Gómez, D., Gaisl, T., Bregy, L., Martínez-Lozano Sinues, P., Kohler, M., & Zenobi, R. (2016). Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath. Chemical Communications, 52(55), 8526–8528. https://doi.org/10.1039/c6cc03070j