Publication: On the function and origin of the avian renal portal shunt and its potential significance throughout evolution
On the function and origin of the avian renal portal shunt and its potential significance throughout evolution
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Buyse, K., Stein, K., De Spiegelaere, W., Cornillie, P., Clauss, M., & Janssens, G. P. J. (2025). On the function and origin of the avian renal portal shunt and its potential significance throughout evolution. Biological Reviews of the Cambridge Philosophical Society, 100(1), 351–361. https://doi.org/10.1111/brv.13144
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All birds possess a unique venous architecture surrounding the kidneys known as the renal portal system. In veterinary medicine, this system is well known for causing a first‐pass effect when medication is administered parenterally via the leg veins, that is venous blood from the leg is filtered before entering general circulation, thus possibly compromising adequate dosage. Additionally, bilateral valves are present in these veins, and it has been hypothesized that they play a crucial role in regulating flow through the kidneys to pr
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Buyse, K., Stein, K., De Spiegelaere, W., Cornillie, P., Clauss, M., & Janssens, G. P. J. (2025). On the function and origin of the avian renal portal shunt and its potential significance throughout evolution. Biological Reviews of the Cambridge Philosophical Society, 100(1), 351–361. https://doi.org/10.1111/brv.13144