Histologic composition of marginal mucosal tissue augmented by a resorbable volume-stable collagen matrix in soft tissue thickening procedures in humans: a morphometric observational study

Artzi, Zvi; Renert, Uri; Netanely, Erez; Thoma, Daniel S; Vered, Marilena

doi:10.1007/s00784-021-04016-1

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Artzi, Z., Renert, U., Netanely, E., Thoma, D. S., & Vered, M. (2022). Histologic composition of marginal mucosal tissue augmented by a resorbable volume-stable collagen matrix in soft tissue thickening procedures in humans: a morphometric observational study. Clinical Oral Investigations, 26(1), 427–435. https://doi.org/10.1007/s00784-021-04016-1

Abstract

AIM This study aims to examine the composition of lining and masticatory mucosa at the pre- and post-soft tissue augmentation procedures with a volume-stable cross-linking collagen matrix (VCMX) in humans. MATERIALS AND METHODS In 12 patients, single implant sites were augmented with a VCMX. Biopsies were obtained including masticatory (MM) and lining (LM) mucosa before augmentation and at 12 weeks post-augmentation procedures. Rete pegs density (RPD), length (RPL), and blood vessel density (BVD) were histomorphometrically analyzed at