Publication: Antibiotic Algae by Chemical Surface Engineering
Antibiotic Algae by Chemical Surface Engineering
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Kerschgens, I. P., & Gademann, K. (2018). Antibiotic Algae by Chemical Surface Engineering. Chembiochem, 19(5), 439–443. https://doi.org/10.1002/cbic.201700553
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Abstract
Chemical cell-surface engineering is a tool for modifying and altering cellular functions. Herein, we report the introduction of an antibiotic phenotype to the green alga Chlamydomonas reinhardtii by chemically modifying its cell surface. Flow cytometry and confocal microscopy studies demonstrated that a hybrid of the antibiotic vancomycin anda4-hydroxyproline oligomer binds reversibly to the cell wall without affecting the viability or motility of the cells. The modified cells were used to inhibit bacterial growth of Gram-positive Ba
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- Kerschgens, Isabel P
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Kerschgens, I. P., & Gademann, K. (2018). Antibiotic Algae by Chemical Surface Engineering. Chembiochem, 19(5), 439–443. https://doi.org/10.1002/cbic.201700553
