Risk Factors for Preterm Birth following Open Fetal Myelomeningocele Repair: Results from a Prospective Cohort

Kahr, Maike Katja; Winder, Franziska; Vonzun, Ladina; Meuli, Martin; Mazzone, Luca; Moehrlen, Ueli; Krähenmann, Franziska; Hüsler, Margaret; Zimmermann, Roland; Ochsenbein-Kölble, Nicole

doi:10.1159/000500048

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Kahr, M. K., Winder, F., Vonzun, L., Meuli, M., Mazzone, L., Moehrlen, U., Krähenmann, F., Hüsler, M., Zimmermann, R., & Ochsenbein-Kölble, N. (2020). Risk Factors for Preterm Birth following Open Fetal Myelomeningocele Repair: Results from a Prospective Cohort. Fetal Diagnosis and Therapy, 47(1), 15–23. https://doi.org/10.1159/000500048

Abstract

BACKGROUND Fetal myelomeningocele (fMMC) repair is a therapeutic option in selected cases. This study aimed to identify risk factors for preterm birth (PTB) following open fMMC repair. METHODS Sixty-seven women underwent fMMC repair and delivered a baby between 2010 and 2018 at our center. Demographic, surgical, and pregnancy complications, including potential risk factors for PTB such as preterm premature rupture of membranes (PPROM), chorioamniotic membrane separation (CMS), and placental abruption were evaluated. RESULTS Maternal b