Publication: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients
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Jarius, S., Lechner, C., Wendel, E. M., Baumann, M., Breu, M., Schimmel, M., Karenfort, M., Marina, A. D., Merkenschlager, A., Thiels, C., Blaschek, A., Salandin, M., Leiz, S., Leypoldt, F., Pschibul, A., Hackenberg, A., Hahn, A., Syrbe, S., Strautmanis, J., … et al. (2020). Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients. Journal of Neuroinflammation, 17(1), 262. https://doi.org/10.1186/s12974-020-01825-1
Abstract
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Background
New-generation, cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprotein (MOG-IgG) with (mostly recurrent) optic neuritis, myelitis, and brainstem encephalitis, as well as with neuromyelitis optica (NMO)-like or acute-disseminated encephalomyelitis (ADEM)-like presentations. However, only limited data are yet available on cerebrospinal fluid (CSF) findings in MOG-IgG-associated encephalomyelitis (MOG-EM; also termed MOG antibody-associated dis
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Creators (Authors)
- Jarius, Sven
- Lechner, Christian
- Wendel, Eva M
- Baumann, Matthias
- Breu, Markus
- Schimmel, Mareike
- Karenfort, Michael
- Marina, Adela Della
- Merkenschlager, Andreas
- Thiels, Charlotte
- Blaschek, Astrid
- Salandin, Michela
- Leiz, Steffen
- Leypoldt, Frank
- Pschibul, Alexander
- Hackenberg, Annette
- Hahn, Andreas
- Syrbe, Steffen
- Strautmanis, Jurgis
- Häusler, Martin
- Krieg, Peter
- Eisenkölbl, Astrid
- Stoffels, Johannes
- Eckenweiler, Matthias
- Ayzenberg, Ilya
- Haas, Jürgen
- Höftberger, Romana
- Kleiter, Ingo
- Korporal-Kuhnke, Mirjam
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Jarius, S., Lechner, C., Wendel, E. M., Baumann, M., Breu, M., Schimmel, M., Karenfort, M., Marina, A. D., Merkenschlager, A., Thiels, C., Blaschek, A., Salandin, M., Leiz, S., Leypoldt, F., Pschibul, A., Hackenberg, A., Hahn, A., Syrbe, S., Strautmanis, J., … et al. (2020). Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients. Journal of Neuroinflammation, 17(1), 262. https://doi.org/10.1186/s12974-020-01825-1
