Publication: Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster.
Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster.
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Morey, M., Serras, F., Baguñà, J., Hafen, E., & Corominas, M. (2001). Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Developmental Biology, 238(1), 145–156. https://doi.org/10.1006/dbio.2001.0389
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Modulation of reactive oxygen species (ROS) plays a key role in signal transduction pathways. Selenoproteins act controlling the redox balance of the cell. We have studied how the alteration of the redox balance caused by patufet (selD(ptuf)), a null mutation in the Drosophila melanogaster selenophosphate synthetase 1 (sps1) gene, which codes for the SelD enzyme of the selenoprotein biosynthesis, affects the Ras/MAPK signalling pathway. The selD(ptuf) mutation dominantly suppresses the phenotypes in the eye and the wing caused by hype
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- Morey, M
- Serras, F
- Baguñà, J
- Hafen, E
- Corominas, M
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Morey, M., Serras, F., Baguñà, J., Hafen, E., & Corominas, M. (2001). Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Developmental Biology, 238(1), 145–156. https://doi.org/10.1006/dbio.2001.0389