Publication: The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release
The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release
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Wueest, S., & Konrad, D. (2018). The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release. Adipocyte, 7(3), 226–228. https://doi.org/10.1080/21623945.2018.1493901
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Abstract
High secretion of interleukin (IL)-6 from white adipose tissue may contribute to metabolic complications in obesity. We have recently shown that IL-6-type cytokine signaling in adipocytes is involved in the development of obesity-associated hepatic insulin resistance and steatosis. In addition, we revealed that adipocyte-specific IL-6 signaling ameliorates glucose metabolism in obesity via enhancing insulin secretion. Mechanistically, IL-6 induces the release of free fatty acid (FFA) and leptin from adipocytes thereby affecting liver
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- Wueest, Stephan
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Wueest, S., & Konrad, D. (2018). The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release. Adipocyte, 7(3), 226–228. https://doi.org/10.1080/21623945.2018.1493901
