Publication: CD26/DPP4 - a potential biomarker and target for cancer therapy
CD26/DPP4 - a potential biomarker and target for cancer therapy
Date
Date
Date
Citations
Enz, N., Vliegen, G., De Meester, I., & Jungraithmayr, W. (2019). CD26/DPP4 - a potential biomarker and target for cancer therapy. Pharmacology & Therapeutics, 198, 135–159. https://doi.org/10.1016/j.pharmthera.2019.02.015
Abstract
Abstract
Abstract
CD26/dipeptidyl peptidase (DPP)4 is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express CD26/DPP4 to a variable extent. By cleaving dipeptides from peptides with a proline or alanine in the penultimate position at the N-terminus, it regulates the activity of incretin hormones, chemokines and many other peptides. Due to these effects and interactions with other molecules, a tumor promoting or s
Metrics
Views
Additional indexing
Creators (Authors)
- Enz, Njanja
- Vliegen, Gwendolyn
- De Meester, Ingrid
- Jungraithmayr, Wolfgang
Volume
Volume
Volume
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Metrics
Views
Citations
Enz, N., Vliegen, G., De Meester, I., & Jungraithmayr, W. (2019). CD26/DPP4 - a potential biomarker and target for cancer therapy. Pharmacology & Therapeutics, 198, 135–159. https://doi.org/10.1016/j.pharmthera.2019.02.015
