Publication:

Mass spectrometric method incorporating enzymatic amplification for attomole-level analysis of target metabolites in biological samples

Date

Date

Date
2010
Journal Article
Published version
Simple data Full metadata Statistics
cris.lastimport.scopus2025-07-12T03:30:29Z
cris.lastimport.wos2025-08-04T01:36:44Z
dc.contributor.institutionUniversity of Zurich
dc.date.accessioned2010-11-04T16:04:52Z
dc.date.available2010-11-04T16:04:52Z
dc.date.issued2010
dc.description.abstract

We report a sensitive method for selective detection of target metabolites from the central metabolic pathway by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS), in which the MS signal is enhanced by up to three orders of magnitude in the course of in situ enzymatic amplification.

dc.identifier.doi10.1039/b925433a
dc.identifier.issn1359-7345
dc.identifier.scopus2-s2.0-77949581377
dc.identifier.urihttps://www.zora.uzh.ch/handle/20.500.14742/53997
dc.identifier.wos000275662100010
dc.language.isoeng
dc.subject.ddc570 Life sciences; biology
dc.subject.ddc610 Medicine & health
dc.title

Mass spectrometric method incorporating enzymatic amplification for attomole-level analysis of target metabolites in biological samples

dc.typearticle
dcterms.accessRightsinfo:eu-repo/semantics/closedAccess
dcterms.bibliographicCitation.journaltitleChemical Communications
dcterms.bibliographicCitation.number13
dcterms.bibliographicCitation.originalpublishernameRoyal Society of Chemistry
dcterms.bibliographicCitation.pageend2214
dcterms.bibliographicCitation.pagestart2212
dcterms.bibliographicCitation.pmid20234909
dcterms.bibliographicCitation.volume46
dspace.entity.typePublicationen
uzh.contributor.affiliationETH Zürich
uzh.contributor.affiliationETH Zürich
uzh.contributor.affiliationETH Zürich
uzh.contributor.affiliationETH Zürich
uzh.contributor.affiliationETH Zürich
uzh.contributor.authorUrban, P L
uzh.contributor.authorAmantonico, A
uzh.contributor.authorFagerer, S R
uzh.contributor.authorGehrig, P
uzh.contributor.authorZenobi, R
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceYes
uzh.document.availabilitycontent_undefined
uzh.eprint.datestamp2010-11-04 16:04:52
uzh.eprint.lastmod2025-08-04 01:47:10
uzh.eprint.statusChange2010-11-04 16:04:52
uzh.harvester.ethYes
uzh.harvester.nbNo
uzh.identifier.doi10.5167/uzh-35676
uzh.jdb.eprintsId17065
uzh.oastatus.unpaywallclosed
uzh.oastatus.zoraClosed
uzh.publication.citationUrban, P L; Amantonico, A; Fagerer, S R; Gehrig, P; Zenobi, R (2010). Mass spectrometric method incorporating enzymatic amplification for attomole-level analysis of target metabolites in biological samples. Chemical Communications, 46(13):2212-2214.
uzh.publication.freeAccessAtrelatedurl
uzh.publication.originalworkoriginal
uzh.publication.publishedStatusfinal
uzh.scopus.impact14
uzh.scopus.subjectsCatalysis
uzh.scopus.subjectsElectronic, Optical and Magnetic Materials
uzh.scopus.subjectsCeramics and Composites
uzh.scopus.subjectsGeneral Chemistry
uzh.scopus.subjectsSurfaces, Coatings and Films
uzh.scopus.subjectsMetals and Alloys
uzh.scopus.subjectsMaterials Chemistry
uzh.workflow.eprintid35676
uzh.workflow.fulltextStatusrestricted
uzh.workflow.revisions140
uzh.workflow.rightsCheckkeininfo
uzh.workflow.statusarchive
uzh.wos.impact13
Files

Original bundle

Name:
2010-02-25.pdf
Size:
1.08 MB
Format:
Adobe Portable Document Format
Downloadable by admins only
2010-02-25.pdfview file |Download1.08 MB
Publication available in collections:
Publications of Functional Genomics Center Zurich
Publications of Systems Biology / Functional Genomics