Publication: NMR spectroscopy of a single mammalian early stage embryo
NMR spectroscopy of a single mammalian early stage embryo
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Sivelli, G., Conley, G. M., Herrera, C., Marable, K., Rodriguez, K. J., Bollwein, H., Sudano, M. J., Brugger, J., Simpson, A. J., Boero, G., & Grisi, M. (2022). NMR spectroscopy of a single mammalian early stage embryo. Journal of Magnetic Resonance, 335, 107142. https://doi.org/10.1016/j.jmr.2021.107142
Abstract
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Abstract
The resolving power, chemical sensitivity and non-invasive nature of NMR have made it an established technique for in vivo studies of large organisms both for research and clinical applications. NMR would clearly be beneficial for analysis of entities at the microscopic scale of about 1 nL (the nanoliter scale), typical of early development of mammalian embryos, microtissues and organoids: the scale where the building blocks of complex organisms could be observed. However, the handling of such small samples (about 100 µm) and sensitiv
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- Sivelli, Giulia
- Conley, Gaurasundar M
- Herrera, Carolina
- Marable, Kathryn
- Rodriguez, Kyle J
- Bollwein, Heinrich
- Sudano, Mateus J
- Brugger, Jürgen
- Simpson, Andre J
- Boero, Giovanni
- Grisi, Marco
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Sivelli, G., Conley, G. M., Herrera, C., Marable, K., Rodriguez, K. J., Bollwein, H., Sudano, M. J., Brugger, J., Simpson, A. J., Boero, G., & Grisi, M. (2022). NMR spectroscopy of a single mammalian early stage embryo. Journal of Magnetic Resonance, 335, 107142. https://doi.org/10.1016/j.jmr.2021.107142
