Publication: Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats
Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats
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Lopez-Ferreras, L., Asker, M., Krieger, J.-P., & Skibicka, K. P. (2023). Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats. Frontiers in Neuroscience, 17, 1265080. https://doi.org/10.3389/fnins.2023.1265080
Abstract
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Abstract
Glucagon-like peptide-1 (GLP-1) analogs represent a new class of weight-loss medication, which has recently exponentially grown in popularity. GLP-1 is produced in the intestinal L cells in response to macronutrient intake, but it is also produced in the brain in a subset of neurons in the nucleus of the solitary tract (NTS). Exogenously-delivered GLP-1 analogs reduce food intake and food-motivated behavior in male and female rats, with some sex divergence of these effects in specific brain sites. These analogs potentially target GLP-
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- Lopez-Ferreras, Lorena
- Asker, Mohammed
- Krieger, Jean-Philippe
- Skibicka, Karolina Patrycja
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Lopez-Ferreras, L., Asker, M., Krieger, J.-P., & Skibicka, K. P. (2023). Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats. Frontiers in Neuroscience, 17, 1265080. https://doi.org/10.3389/fnins.2023.1265080
