Publication: Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro
Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro
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Lionetto, S., Little, A., Moriceau, G., Heymann, D., Decurtins, M., Plecko, M., Filgueira, L., & Cadosch, D. (2013). Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro. Journal of Biomedical Materials Research. Part A, 101A(4), 991–997. https://doi.org/10.1002/jbm.a.34402
Abstract
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In vitro studies suggest that human osteoclasts (OC) are able to corrode surgical stainless steel 316L (SS). The aim of this study was to investigate whether osteoclastic biocorrosion can be blocked pharmacologically. Human OCs were generated in vitro from peripheral blood monocytic cells (PBMCs) in the presence of OC differentiation cytokines. The osteoclastic viability, differentiation, and resorptive function (on both bone and SS) were assessed using standard colorimetric cell viability assay 3-(4,5-dimethylthiazol-2-yl)-5-(3-carbo
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- Little, A
- Moriceau, G
- Heymann, D
- Decurtins, M
- Plecko, M
- Filgueira, L
- Cadosch, D
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Lionetto, S., Little, A., Moriceau, G., Heymann, D., Decurtins, M., Plecko, M., Filgueira, L., & Cadosch, D. (2013). Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro. Journal of Biomedical Materials Research. Part A, 101A(4), 991–997. https://doi.org/10.1002/jbm.a.34402