Publication: Side Effects 15 Years After Lymph Node Irradiation in Breast Cancer: Randomized EORTC Trial 22922/10925
Side Effects 15 Years After Lymph Node Irradiation in Breast Cancer: Randomized EORTC Trial 22922/10925
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Poortmans, P. M., Struikmans, H., De Brouwer, P., Weltens, C., Fortpied, C., Kirkove, C., Budach, V., Peignaux-Casasnovas, K., van der Leij, F., Vonk, E., Valli, M., vanTienhoven, G., Weidner, N., Noel, G., Guckenberger, M., Koiter, E., vanLimbergen, E., Engelen, A., Fourquet, A., & Bartelink, H. (2021). Side Effects 15 Years After Lymph Node Irradiation in Breast Cancer: Randomized EORTC Trial 22922/10925. Journal of the National Cancer Institute, 113(10), 1360–1368. https://doi.org/10.1093/jnci/djab113
Abstract
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BACKGROUND
Uncertainty about the benefit-risk ratio of regional lymph node irradiation led to varying clinical protocols. We investigated long-term late side effects after internal mammary and medial supraclavicular (IM-MS) lymph node irradiation to improve shared decision making.
METHODS
The multicenter European Organization for Research and Treatment of Cancer trial (ClinicalTrials.gov, NCT00002851) randomly assigned stage I-III breast cancer patients with involved axillary nodes and/or a medially located primary tumor. We analyz
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Creators (Authors)
- Poortmans, Philip M
- Struikmans, Henk
- De Brouwer, Peter
- Weltens, Caroline
- Fortpied, Catherine
- Kirkove, Carine
- Budach, Volker
- Peignaux-Casasnovas, Karine
- van der Leij, Femke
- Vonk, Ernest
- Valli, Mariacarla
- vanTienhoven, Geertjan
- Weidner, Nicola
- Noel, Georges
- Guckenberger, Matthias
- Koiter, Eveline
- vanLimbergen, Erik
- Engelen, Antoine
- Fourquet, Alain
- Bartelink, Harry
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Poortmans, P. M., Struikmans, H., De Brouwer, P., Weltens, C., Fortpied, C., Kirkove, C., Budach, V., Peignaux-Casasnovas, K., van der Leij, F., Vonk, E., Valli, M., vanTienhoven, G., Weidner, N., Noel, G., Guckenberger, M., Koiter, E., vanLimbergen, E., Engelen, A., Fourquet, A., & Bartelink, H. (2021). Side Effects 15 Years After Lymph Node Irradiation in Breast Cancer: Randomized EORTC Trial 22922/10925. Journal of the National Cancer Institute, 113(10), 1360–1368. https://doi.org/10.1093/jnci/djab113
