Publication: Melanocortin-4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats
Melanocortin-4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats
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Jerjen, C. P., Kumaran, S. J., Liesegang, A., Hall, E., Wichert, B., & Haase, B. (2023). Melanocortin-4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats. Animal Genetics, 54, 637–642. https://doi.org/10.1111/age.13335
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Obesity is an escalating global health problem affecting both humans and companion animals. In cats it is associated with increased mortality and multiple diseases, including diabetes mellitus. Two genes coding for proteins known to play a critical role in energy homeostasis across species are the proopiomelanocortin (POMC) gene and the melanocortin-4 receptor (MC4R) gene. A missense variant in the coding sequence of the feline MC4R (MC4R:c.92C>T) has been reported to be associated with diabetes and overweight in domestic shorthair ca
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- Jerjen, C P
- Kumaran, S J
- Liesegang, Annette
- Hall, E
- Wichert, Brigitta
- Haase, B
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Jerjen, C. P., Kumaran, S. J., Liesegang, A., Hall, E., Wichert, B., & Haase, B. (2023). Melanocortin-4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats. Animal Genetics, 54, 637–642. https://doi.org/10.1111/age.13335
