Publication: Syntheses of bifunctional 2,3-diamino propionic acid-based chelators as small and strong tripod ligands for the labelling of biomolecules with (99m)Tc
Date
Date
Date
2010
Journal Article
Published version
Abstract
Abstract
Abstract
The labelling of targeting biomolecules requires small and hydrophilic complexes in order to not affect the binding properties of the vectors. 2,3-Diamino propionic acid (dap) is a small and strong, albeit scarcely used, tripod ligand for the fac-Tc-99m(CO)(3)](+) moiety. We have introduced at the alpha-carbon atom in the basic dap structure various second functionalities such as carboxylato, amino and alpha-amino acid groups via various spacers in order to yield bifunctional chelators. These dap derivatives can be coupled to targetin
Metrics
Views
140 since deposited on 2011-02-23
Acq. date: 2025-11-12
Additional indexing
Creators (Authors)
- Liu, Y
- Oliveira, B L
- Correia, J D G
- Santos, I C
Volume
Volume
Volume
8
Number
Number
Number
12
Page range/Item number
Page range/Item number
Page range/Item number
2829
Page end
Page end
Page end
2839
Item Type
Item Type
Item Type
Journal Article
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2010
Date available
Date available
Date available
2011-02-23
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1477-0520
OA Status
OA Status
OA Status
Closed
Publisher DOI
Other Identification Number
Other Identification Number
Other Identification Number
ISI:000278964600020
Metrics
Views
140 since deposited on 2011-02-23
Acq. date: 2025-11-12
Closed
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