Publication: Early termination of pivotal trials in Alzheimer's disease—Preserving optimal value for participants and science
Early termination of pivotal trials in Alzheimer's disease—Preserving optimal value for participants and science
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Gietl, A. F., & Frisoni, G. B. (2022). Early termination of pivotal trials in Alzheimer’s disease—Preserving optimal value for participants and science. Alzheimer’s & Dementia, 18(10), 1980–1987. https://doi.org/10.1002/alz.12605
Abstract
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Abstract
Participants in Alzheimer's disease late‐phase clinical trials are frequently confronted with a situation of early termination. We discuss measures to protect the perceived value of study participation and to maximize the scientific value under such circumstances. A communication strategy should ensure that trial participants maintain a positive relationship with the research team and have their informational needs optimally met. Measures to maximize the scientific value may include data/sample sharing, strategies for personalized med
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- Gietl, Anton F
- Frisoni, Giovanni B
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Gietl, A. F., & Frisoni, G. B. (2022). Early termination of pivotal trials in Alzheimer’s disease—Preserving optimal value for participants and science. Alzheimer’s & Dementia, 18(10), 1980–1987. https://doi.org/10.1002/alz.12605
