Publication: Cycling empirical antibiotic therapy in hospitals: Meta-analysis and models
Cycling empirical antibiotic therapy in hospitals: Meta-analysis and models
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Abel zur Wiesch, P., Kouyos, R., Abel, S., Viechtbauer, W., & Bonhoeffer, S. (2014). Cycling empirical antibiotic therapy in hospitals: Meta-analysis and models. PLoS Pathogens, 10(6), e1004225. https://doi.org/10.1371/journal.ppat.1004225
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Abstract
The rise of resistance together with the shortage of new broad-spectrum antibiotics underlines the urgency of optimizing the use of available drugs to minimize disease burden. Theoretical studies suggest that coordinating empirical usage of antibiotics in a hospital ward can contain the spread of resistance. However, theoretical and clinical studies came to different conclusions regarding the usefulness of rotating first-line therapy (cycling). Here, we performed a quantitative pathogen-specific meta-analysis of clinical studies compa
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- Abel zur Wiesch, Pia
- Kouyos, Roger
- Abel, Sören
- Viechtbauer, Wolfgang
- Bonhoeffer, Sebastian
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Abel zur Wiesch, P., Kouyos, R., Abel, S., Viechtbauer, W., & Bonhoeffer, S. (2014). Cycling empirical antibiotic therapy in hospitals: Meta-analysis and models. PLoS Pathogens, 10(6), e1004225. https://doi.org/10.1371/journal.ppat.1004225
