Publication: Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature
Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature
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Mengozzi, A., Costantino, S., Mongelli, A., Mohammed, S. A., Gorica, E., Delfine, V., Masi, S., Virdis, A., Ruschitzka, F., & Paneni, F. (2023). Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature. International Journal of Molecular Sciences, 24(5), 4854. https://doi.org/10.3390/ijms24054854
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Abstract
Systemic arterial hypertension (AH) is a multifaceted disease characterized by accelerated vascular aging and high cardiometabolic morbidity and mortality. Despite extensive work in the field, the pathogenesis of AH is still incompletely understood, and its treatment remains challenging. Recent evidence has shown a deep involvement of epigenetic signals in the regulation of transcriptional programs underpinning maladaptive vascular remodeling, sympathetic activation and cardiometabolic alterations, all factors predisposing to AH. Afte
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- Mengozzi, Alessandro
- Costantino, Sarah
- Mongelli, Alessia
- Mohammed, Shafeeq A
- Gorica, Era
- Delfine, Valentina
- Masi, Stefano
- Virdis, Agostino
- Ruschitzka, Frank
- Paneni, Francesco
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Mengozzi, A., Costantino, S., Mongelli, A., Mohammed, S. A., Gorica, E., Delfine, V., Masi, S., Virdis, A., Ruschitzka, F., & Paneni, F. (2023). Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature. International Journal of Molecular Sciences, 24(5), 4854. https://doi.org/10.3390/ijms24054854
