Past studies have shown strong associations between sexual functioning and interpersonal factors. The aim of this pilot study was to investigate the moderating role of partner-related fascination - an important dimension of relationship quality - in the association between sexual functioning and relationship satisfaction in a community sample of Swiss men and women. A total of 70 individuals participated in an anonymous online survey. Variables related to sexual functioning, fascination and relationship satisfaction were subject to correlation, regression and moderation analyses. Relationship satisfaction and fascination for the partner correlated significantly with sexual functioning in females only (r = .31 to .58). No significant correlations could be observed in men. In women, fascination had a moderating effect on the association between relationship satisfaction and sexual functioning (p <.05). In men, no moderating effect of fascination could be detected. The findings offer evidence for a more complex model of women's sexuality that rests on emotional, contextual and motivational factors. It can be argued that women need a certain level of fascination, closeness and intimacy to enjoy a healthy sexuality. Overall, the findings highlight the importance of addressing gender differences and contextual factors for successful treatment and counseling of sexual problems.