Abstract
In a finding that highlights ways to optimize the efficacy of antibody-based therapeutics and vaccines, the activity of potent HIV-1-neutralizing antibodies has been confirmed to depend on cellular binding to the antibodies’ Fc regions.
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Trkola, A (2014). Potency needs constancy. Nature, 514(7523):442-443.
In a finding that highlights ways to optimize the efficacy of antibody-based therapeutics and vaccines, the activity of potent HIV-1-neutralizing antibodies has been confirmed to depend on cellular binding to the antibodies’ Fc regions.
Item Type: | Journal Article, refereed, further contribution |
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Communities & Collections: | 04 Faculty of Medicine > Institute of Medical Virology |
Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health |
Scopus Subject Areas: | Health Sciences > Multidisciplinary |
Language: | English |
Date: | 23 October 2014 |
Deposited On: | 04 Feb 2015 10:04 |
Last Modified: | 12 Sep 2024 01:37 |
Publisher: | Nature Publishing Group |
ISSN: | 0028-0836 |
OA Status: | Closed |
Publisher DOI: | https://doi.org/10.1038/514442a |
Related URLs: | http://www.nature.com/nature/journal/v514/n7523/pdf/514442a.pdf (Publisher) |
PubMed ID: | 25341782 |