Navigation auf zora.uzh.ch

Search ZORA

ZORA (Zurich Open Repository and Archive)

A plant-derived wound therapeutic for cost-effective treatment of post-surgical scalp wounds with exposed bone

Läuchli, Severin; Vannotti, Stefanie; Hafner, Jürg; Hunziker, Thomas; French, Lars (2014). A plant-derived wound therapeutic for cost-effective treatment of post-surgical scalp wounds with exposed bone. Forschende Komplementärmedizin, 21(2):88-93.

Abstract

BACKGROUND: To evaluate efficacy and cost-effectiveness of a plant-derived wound dressing (ONE), a mixture of hypericum oil (Hypericum perforatum L.) and neem oil (Azadirachta indica A. Juss.), in scalp wounds with exposed bone.
PATIENTS AND METHODS: All patients with scalp wounds with exposed bone, following the excision of skin tumors, and treated with ONE in 2011 were included. Time of healing, wound size, area of exposed bone, ease of handling, pain, and complications were evaluated. Costs of dressings and nursing time were compared with those cited in literature for other treatment modalities.
RESULTS: Fifteen consecutive patients with a mean age of 76.87 ± 10.3 years (59-90 years) were analyzed. The mean wound size was 10.9 ± 6.84 cm(2) (0.4-22.6 cm(2)) with 4.8 ± 5.9 cm(2) (0.3-20.7 cm(2)) of exposed bone. The time of complete healing by secondary intention was 8.1 (4-20) weeks. Rapid formation of granulation tissue was observed which after 4 weeks covered the entire exposed bone surface in 11 of 15 cases (73%). Dressing change was simple with no pain reported; no infections or other complications occurred. Using ONE for a mean healing time of 56.7 days resulted in mean costs of EUR 423.73, which is substantially lower than those published for fascia lata, negative pressure therapy, or collagen matrix followed by skin grafting (EUR 1,612.82, EUR 4,411.80 and EUR 1,503.72, respectively).
CONCLUSION: This retrospective, non-controlled analysis supports ONE as a simple-to-use and safe treatment option for scalp wounds with exposed bone. Treatment costs compare favorably to those published for other treatment modalities.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Complementary and Alternative Medicine
Language:English
Date:2014
Deposited On:26 Feb 2015 11:47
Last Modified:07 Nov 2024 04:32
Publisher:Karger
ISSN:1661-4119
OA Status:Green
Publisher DOI:https://doi.org/10.1159/000360782
PubMed ID:24851844
Download PDF  'A plant-derived wound therapeutic for cost-effective treatment of post-surgical scalp wounds with exposed bone'.
Preview
  • Content: Published Version

Metadata Export

Statistics

Citations

Dimensions.ai Metrics
13 citations in Web of Science®
16 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

356 downloads since deposited on 26 Feb 2015
59 downloads since 12 months
Detailed statistics

Authors, Affiliations, Collaborations

Similar Publications