Abstract
BACKGROUND: To assess the effect of concomitant subgingival rinsing with 10% PVP-iodine during subgingival instrumentation on the prevalence and magnitude of bacteremia of oral origin.
MATERIALS AND METHODS: Subgingival instrumentation was performed with water or PVP-iodine rinse in patients with periodontitis. Prior to instrumentation, subjects gargled for 1 min with the allocated liquid. Pockets were then rinsed for 1 min and subgingivally instrumented with liquid-cooled (water/PVP-iodine) ultrasonic scalers (1 min). Two minutes later, a blood sample from the arm vein was drawn using a lysis centrifugation blood culture system for quantitative microbiological analysis. Non-parametric statistical tests were performed to assess differences in the prevalence and extent of bacteremia between groups.
RESULTS: Of the 19 samples in each group, oral-borne bacteremia was detected in 10 of the control and 2 of the test samples. With an average of 3.0 [1;5] colony forming units, significantly less bacteria and bacteremia were found in the test group compared to the controls (12.2 [1;46]) (p=0.003). Anaerobic bacteria were not found in the test group.
CONCLUSIONS: Bacteremia after subgingival instrumentation with concomitant PCP-iodine rinsing is reduced but not eliminated. Therefore, it might be recommended for patients at a high risk of endocarditis or infection of endoprostheses. However, preventive antibiotic treatment should not be omitted. This article is protected by copyright. All rights reserved.