he aim of the paper is fourfold: (a) show why humor scholars should study irony, (b) explore the need for considering interindividual differences in healthy adults’ irony performance, (c) stress the necessity for developing tools assessing habitual differences in irony performance, and (d) indicate future directions for joint irony and humor research and outline possible applications. Verbal irony is often employed with a benevolent humorous intent by speakers, but can also serve as a means of disparagement humor. In both cases, encoding and decoding activities entailing irony need to be considered in the context of the psychology of humor. We argue that verbal irony performance can be considered a phenomenon native to the realm of humor and individual differences. We point out that research has widely neglected the meaningfulness of variance in irony performance within experimental groups when looking at determinants of irony detection and production. Based on theoretical considerations and previous empirical findings we show that this variance can be easily related to individual-differences variables such as the sense of humor, dispositions toward laughter and ridicule (e.g., gelotophobia), and general mental ability. Furthermore, we hypothesize that there is an enduring trait determining irony performance we will label the sense of irony. The sense of irony possibly goes along with inclinations toward specific affective and cognitive processing patterns when dealing with verbal irony. As an application, novel irony performance tests can help to study psychological and neurophysiological correlates of irony performance more feasibly, that is, in nonclinical groups.