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Comparison of tissue oximeters on a liquid phantom with adjustable optical properties

Kleiser, S; Nasseri, N; Andresen, B; Greisen, G; Wolf, M (2016). Comparison of tissue oximeters on a liquid phantom with adjustable optical properties. Biomedical Optics Express, 7(8):2973-2992.

Abstract

The SafeBoosC trial showed that cerebral oximetry combined with a treatment guideline can reduce the the burden of hypoxia in neonates by 50% [Brit. Med. J.350, g7635 (2015)]. However, guidelines based on oximetry by one oximeter are not directly usable by other oximeters. We made a blood-lipid phantom simulating the neonatal head to determine the relation between oxygenation values obtained by different oximeters. We calculated coefficients for easy conversion from one oximeter to the other. We additionally determined the corresponding SafeBoosC intervention thresholds at which we measured an uncertainty of up to 9.2% when varying hemoglobin content from 25μM to 70μM. In conclusion, this paper makes the comparison of absolute values obtained by different oximeters possible.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Biotechnology
Physical Sciences > Atomic and Molecular Physics, and Optics
Language:English
Date:1 August 2016
Deposited On:27 Sep 2016 08:17
Last Modified:15 Mar 2025 02:37
Publisher:Optical Society of America
ISSN:2156-7085
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1364/BOE.7.002973
PubMed ID:27570691
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