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Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations


Palermo, Giulia; Miao, Yinglong; Walker, Ross C; Jinek, Martin; McCammon, J Andrew (2016). Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations. ACS Central Science, 2(10):756-763.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Department of Biochemistry
07 Faculty of Science > Department of Biochemistry
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Physical Sciences > General Chemistry
Physical Sciences > General Chemical Engineering
Language:English
Date:2016
Deposited On:10 Nov 2016 10:51
Last Modified:26 Jan 2022 10:15
Publisher:American Chemical Society (ACS)
ISSN:2374-7951
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1021/acscentsci.6b00218
PubMed ID:27800559
Project Information:
  • : FunderSNSF
  • : Grant IDP300PA_164698
  • : Project TitleUnraveling the mechanistic bases of the CRISPR/Cas9 system via computational methods
  • Content: Published Version