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Lipase processing of complex lipid antigens


Sander, Peter; Becker, Katja; Molin, Michael Dal (2016). Lipase processing of complex lipid antigens. Cell Chemical Biology, 23(9):1044-1046.

Abstract

Mycobacterium tuberculosis synthesizes a wide variety of complex lipids that can serve as antigens in immune recognition of the bacterium. In this issue of Cell Chemical Biology, Gilleron et al. (2016) identify key enzymes essential for lipid antigen processing, which is required for CD1b-restricted T cell activation.

Abstract

Mycobacterium tuberculosis synthesizes a wide variety of complex lipids that can serve as antigens in immune recognition of the bacterium. In this issue of Cell Chemical Biology, Gilleron et al. (2016) identify key enzymes essential for lipid antigen processing, which is required for CD1b-restricted T cell activation.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Life Sciences > Biochemistry
Life Sciences > Molecular Medicine
Life Sciences > Molecular Biology
Life Sciences > Pharmacology
Life Sciences > Drug Discovery
Life Sciences > Clinical Biochemistry
Language:English
Date:22 September 2016
Deposited On:15 Dec 2016 14:19
Last Modified:30 Jul 2020 23:13
Publisher:Cell Press (Elsevier)
ISSN:2451-9456
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.chembiol.2016.09.005
PubMed ID:27662250

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