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Leutert, Mario; Pedrioli, Deena M Leslie; Hottiger, Michael O (2016). Identification of PARP-specific ADP-ribosylation targets reveals a regulatory function for ADP-ribosylation in transcription elongation. Molecular Cell, 63(2):181-183.
In a recent issue of Science, Gibson et al. (2016) describe an in vitro chemical genetic approach that maps the specific ADP-ribosylation sites targeted by the ADP-ribosyltransferases PARP-1, PARP-2, and PARP-3 and demonstrate that PARP-1 regulates RNA polymerase II promoter-proximal pausing.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 05 Vetsuisse Faculty > Veterinärwissenschaftliches Institut > Department of Molecular Mechanisms of Disease
07 Faculty of Science > Department of Molecular Mechanisms of Disease |
| Dewey Decimal Classification: | 570 Life sciences; biology |
| Scopus Subject Areas: | Life Sciences > Molecular Biology
Life Sciences > Cell Biology |
| Language: | English |
| Date: | 21 July 2016 |
| Deposited On: | 16 Dec 2016 09:41 |
| Last Modified: | 15 May 2025 01:38 |
| Publisher: | Cell Press (Elsevier) |
| ISSN: | 1097-2765 |
| OA Status: | Closed |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1016/j.molcel.2016.07.006 |
| PubMed ID: | 27447982 |
Leutert, Mario