Header

UZH-Logo

Maintenance Infos

New linear polyamine derivatives in spider venoms


Tzouros, Manuel; Chesnov, Sergiy; Bienz, Stefan; Hesse, Manfred; Bigler, Laurent (2005). New linear polyamine derivatives in spider venoms. Toxicon, 46(3):350-354.

Abstract

Linear free polyamines were characterized in the venom of the spiders Agelenopsis aperta, Hololena curta, and Paracoelotes
birulai by RP-HPLC coupled to mass spectrometry. The several linear polyamines found were tetramine, pentamine, and
hexamine derivatives. Some of these natural products were identified as N-hydroxylated, guanidylated, or acetylated
compounds. In addition, the biosynthetical pathway leading to the formation of acylpolyamines in spider venoms is discussed.

Abstract

Linear free polyamines were characterized in the venom of the spiders Agelenopsis aperta, Hololena curta, and Paracoelotes
birulai by RP-HPLC coupled to mass spectrometry. The several linear polyamines found were tetramine, pentamine, and
hexamine derivatives. Some of these natural products were identified as N-hydroxylated, guanidylated, or acetylated
compounds. In addition, the biosynthetical pathway leading to the formation of acylpolyamines in spider venoms is discussed.

Statistics

Citations

Dimensions.ai Metrics
13 citations in Web of Science®
11 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

0 downloads since deposited on 24 Aug 2017
0 downloads since 12 months

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Scopus Subject Areas:Life Sciences > Toxicology
Uncontrolled Keywords:Spider toxins, APCI, MS/MS, Triple quadrupole, Gas-phase fragmentation
Language:English
Date:2005
Deposited On:24 Aug 2017 14:42
Last Modified:31 Jul 2020 01:14
Publisher:Elsevier
ISSN:0041-0101
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.toxicon.2005.04.018
PubMed ID:15982700

Download

Closed Access: Download allowed only for UZH members

Content: Published Version
Language: English
Filetype: PDF - Registered users only
Size: 182kB
View at publisher