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Timing of definitive fixation of major long bone fractures: can fat embolism syndrome be prevented?


Blokhuis, Taco J; Pape, Hans-Christoph; Frölke, Jan-Paul (2017). Timing of definitive fixation of major long bone fractures: can fat embolism syndrome be prevented? Injury, 48(Suppl 1):S3-S6.

Abstract

Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures.

Abstract

Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Department of Trauma Surgery
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Damage control orthopaedics, Fat embolism, Fat embolism syndrome, Femur fracture, Safe Definitive Surgery (SDS)
Language:German
Date:June 2017
Deposited On:17 Oct 2017 16:01
Last Modified:19 Feb 2018 08:55
Publisher:Elsevier
ISSN:0020-1383
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.injury.2017.04.015
PubMed ID:28449860

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