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Systematic review of lymphovenous anastomosis (LVA) for the treatment of lymphedema

Scaglioni, Mario F; Fontein, Duveken B Y; Arvanitakis, Michael; Giovanoli, Pietro (2017). Systematic review of lymphovenous anastomosis (LVA) for the treatment of lymphedema. Microsurgery, 37(8):947-953.

Abstract

INTRODUCTION: Lymphedema is a chronic condition caused by the obstruction or impairment of lymphatic fluid transport resulting in irreversible skin fibrosis. Besides conservative therapy, surgical techniques for lymphedema including liposuction, lymphatico-lymphatic bypass, lymphovenous anastomosis (LVA), and vascularized lymph node transfer (VLNT) are options with increasing popularity in the recent past. In our review, we investigated the efficacy of LVA for the treatment of lymphedema. Both objective and subjective outcomes of surgical treatment were evaluated.
METHODS: Studies were identified through systematic review in PubMed database up to September 2016. Only original Articles which exclusively performed LVA for lymphedema treatment were included. Our primary endpoint was the objective of a subjective postoperative lymphedema reduction.
RESULTS: A total of 293 titles were identified, out of which 18 studies including 939 patients were deemed eligible. The studies included in this review describe significant variations in surgical techniques, number of anastomoses and supplementary interventions. All studies reported objective reductions in circumference measurements. Subjective symptom relief was found in 50-100% of the patients as well as a reduction in the number of cellulitis episodes in all investigated cases.
CONCLUSION: Although the studies included in this review showed great heterogeneity, LVA surgery revealed both objective and subjective improvements in most patients.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Surgery
Uncontrolled Keywords:LVA, lymphatic surgery, lymphedema surgery, lymphovenous anastomosis, lymphovenous bypass operation
Language:English
Date:November 2017
Deposited On:20 Dec 2017 14:38
Last Modified:18 Feb 2025 04:40
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0738-1085
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/micr.30246
PubMed ID:28972280

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