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Biology of the Microbiome 1: Interactions with the Host Immune Response

Smolinska, Sylwia; Groeger, David; O'Mahony, Liam (2017). Biology of the Microbiome 1: Interactions with the Host Immune Response. Gastroenterology clinics of North America, 46(1):19-35.

Abstract

The intestinal immune system is intimately connected with the vast diversity of microbes present within the gut and the diversity of food components that are consumed daily. The discovery of novel molecular mechanisms, which mediate host-microbe-nutrient communication, have highlighted the important roles played by microbes and dietary factors in influencing mucosal immune responses. Dendritic cells, epithelial cells, innate lymphoid cells, T regulatory cells, effector lymphocytes, natural killer T cells, and B cells can all be influenced by the microbiome. Many of the mechanisms being described are bacterial strain or metabolite specific.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Swiss Institute of Allergy and Asthma Research
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Gastroenterology
Language:English
Date:March 2017
Deposited On:26 Jan 2018 08:55
Last Modified:19 Feb 2025 04:43
Publisher:Elsevier
ISSN:0889-8553
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.gtc.2016.09.004
PubMed ID:28164850
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