Header

UZH-Logo

Maintenance Infos

Biology of the Microbiome 1: Interactions with the Host Immune Response


Smolinska, Sylwia; Groeger, David; O’Mahony, Liam (2017). Biology of the Microbiome 1: Interactions with the Host Immune Response. Gastroenterology clinics of North America, 46(1):19-35.

Abstract

The intestinal immune system is intimately connected with the vast diversity of microbes present within the gut and the diversity of food components that are consumed daily. The discovery of novel molecular mechanisms, which mediate host-microbe-nutrient communication, have highlighted the important roles played by microbes and dietary factors in influencing mucosal immune responses. Dendritic cells, epithelial cells, innate lymphoid cells, T regulatory cells, effector lymphocytes, natural killer T cells, and B cells can all be influenced by the microbiome. Many of the mechanisms being described are bacterial strain or metabolite specific.

Abstract

The intestinal immune system is intimately connected with the vast diversity of microbes present within the gut and the diversity of food components that are consumed daily. The discovery of novel molecular mechanisms, which mediate host-microbe-nutrient communication, have highlighted the important roles played by microbes and dietary factors in influencing mucosal immune responses. Dendritic cells, epithelial cells, innate lymphoid cells, T regulatory cells, effector lymphocytes, natural killer T cells, and B cells can all be influenced by the microbiome. Many of the mechanisms being described are bacterial strain or metabolite specific.

Statistics

Citations

Dimensions.ai Metrics
6 citations in Web of Science®
7 citations in Scopus®
9 citations in Microsoft Academic
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Swiss Institute of Allergy and Asthma Research
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:March 2017
Deposited On:26 Jan 2018 08:55
Last Modified:19 Feb 2018 10:33
Publisher:Elsevier
ISSN:0889-8553
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.gtc.2016.09.004
PubMed ID:28164850

Download

Full text not available from this repository.
View at publisher

Get full-text in a library