Abstract
Platelet inhibition represents the cornerstone of cardiovascular therapy, owing to the central role of platelets in the genesis of acute ischaemic events. The aim of this article is to review current evidence and trends in coronary dual antiplatelet therapy (DAPT), such as preloading in patients with an acute coronary syndrome, optimal duration of DAPT after stent implantation and indications for long-term treatment, to provide an overview on the role of DAPT following percutaneous valve and structural interventions, and an update on the most recent information concerning the concomitant use of DAPT and oral anticoagulation. A short glance into future perspectives and trends in DAPT will be given.
Biasco, Luigi