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Ultraschnelle zelluläre Anpassung an Schwerelosigkeit


Thiel, Cora; Hock, Bertold; Ullrich, Oliver (2017). Ultraschnelle zelluläre Anpassung an Schwerelosigkeit. Flugmedizin - Tropenmedizin - Reisemedizin, 24(04):170-175.

Abstract

Real-time on-orbit measurements at the International Space Station (ISS) could demonstrate that cells are in principle capable of ultimately adapting to microgravity conditions. In the experiment TRIPLE LUX A, the influence of gravitational forces between 1 and 0 g on the oxidative burst reaction of NR8383 alveolar macrophages was investigated. For the first time, a gravity-dependent reaction in mammalian cells could be directly demonstrated and followed by real-time and on-orbit measurements at the ISS. As a result of the measurement setup, the detection of a fast and complete adaptation of a cellular response to microgravity was achieved.

Abstract

Real-time on-orbit measurements at the International Space Station (ISS) could demonstrate that cells are in principle capable of ultimately adapting to microgravity conditions. In the experiment TRIPLE LUX A, the influence of gravitational forces between 1 and 0 g on the oxidative burst reaction of NR8383 alveolar macrophages was investigated. For the first time, a gravity-dependent reaction in mammalian cells could be directly demonstrated and followed by real-time and on-orbit measurements at the ISS. As a result of the measurement setup, the detection of a fast and complete adaptation of a cellular response to microgravity was achieved.

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Additional indexing

Item Type:Journal Article, not_refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Anatomy
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:German
Date:2017
Deposited On:23 Feb 2018 15:33
Last Modified:14 Mar 2018 17:47
Publisher:Georg Thieme Verlag
ISSN:1864-4538
OA Status:Closed
Publisher DOI:https://doi.org/10.1055/s-0043-115673

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