Abstract
Real-time on-orbit measurements at the International Space Station (ISS) could demonstrate that cells are in principle capable of ultimately adapting to microgravity conditions. In the experiment TRIPLE LUX A, the influence of gravitational forces between 1 and 0 g on the oxidative burst reaction of NR8383 alveolar macrophages was investigated. For the first time, a gravity-dependent reaction in mammalian cells could be directly demonstrated and followed by real-time and on-orbit measurements at the ISS. As a result of the measurement setup, the detection of a fast and complete adaptation of a cellular response to microgravity was achieved.
Thiel, Cora