Aim of this paper was to investigate the change in masticatory muscle forces and temporomandibular joint (TMJ) reaction forces simulated by inverse dynamics when the steepness of the anterior fossa slope was varied. We used the model by de Zee et al. (2007) created in AnyBody™. The model was equipped with 24 musculotendon actuators. Mandibular movement was governed by the trajectory of the incisal point. The TMJ was modelled as a planar constraint canted 5° medially and the caudal inclination relative to the occlusal plane was varied from 10° to 70°. Our models showed that for the two simulated movements (empty chewing and unilateral clenching) the joint reaction forces were smallest for the eminence inclination of 30° and 40° and highest for 70°. The muscle forces were relatively insensitive to change of the eminence inclination for the angles between 20° and 50°. This did not hold for the pterygoid muscle, for which the muscle forces increased continually with increasing fossa inclination. For empty chewing the muscle force reached smaller values than for clenching. During clenching, the muscle forces changed by up to 200N.