Abstract
- Animal studies have improved the understanding of SAH pathophysiology
- Intravascular catheters are associated with increased risk of thrombosis
- Larger retrospective case series show that TTM is a last resort treatment of intracranial hypertension and vasospasm
- Findings in a recent prospective pilot study showed that TTM treatment can be beneficial in high-grade SAH patients
- A prospective randomized study in high-grade patients with prophylactic TTM is needed and should include a few centres with a very strictly controlled treatment protocol