Header

UZH-Logo

Maintenance Infos

HIV and Aging - Perhaps Not as Dramatic as We Feared?


Engel, Tanja; Raffenberg, Marieke; Marzolini, Catia; Cavassini, Matthias; Kovari, Helen; Hasse, Barbara; Tarr, Philip E (2018). HIV and Aging - Perhaps Not as Dramatic as We Feared? Gerontology, 64(5):446-456.

Abstract

Ever since the introduction of highly active antiretroviral therapy (ART) in 1995, HIV infection has been linked to "metabolic" complications (insulin resistance, dyslipidemia, osteoporosis, and others). Studies suggested increased rates of myocardial infarction, renal insufficiency, neurocognitive dysfunction, and fractures in HIV-postitive patients. Even long-term suppression of HIV seemed to be accompanied by an excess of deleterious inflammation that could promote these complications. The aims of this viewpoint paper are to summarize recent data and to examine the possibility that the problem of aging-related morbidity in HIV might not be as dramatic as previously believed.

Abstract

Ever since the introduction of highly active antiretroviral therapy (ART) in 1995, HIV infection has been linked to "metabolic" complications (insulin resistance, dyslipidemia, osteoporosis, and others). Studies suggested increased rates of myocardial infarction, renal insufficiency, neurocognitive dysfunction, and fractures in HIV-postitive patients. Even long-term suppression of HIV seemed to be accompanied by an excess of deleterious inflammation that could promote these complications. The aims of this viewpoint paper are to summarize recent data and to examine the possibility that the problem of aging-related morbidity in HIV might not be as dramatic as previously believed.

Statistics

Citations

Dimensions.ai Metrics

Altmetrics

Downloads

18 downloads since deposited on 26 Jun 2018
17 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Ageing, Geriatrics and Gerontology
Language:English
Date:15 June 2018
Deposited On:26 Jun 2018 11:52
Last Modified:24 Sep 2019 23:31
Publisher:Karger
ISSN:0304-324X
OA Status:Green
Publisher DOI:https://doi.org/10.1159/000489172
PubMed ID:29909411

Download

Green Open Access

Download PDF  'HIV and Aging - Perhaps Not as Dramatic as We Feared?'.
Preview
Content: Published Version
Filetype: PDF
Size: 1MB
View at publisher