Header

UZH-Logo

Maintenance Infos

CME: Kardiovaskuläres Screening: Sinn, Unsinn und Bedeutung der Bestimmung von Lipoprotein(a)


Jonas, Henriette; Annema, Wijtske; von Eckardstein, Arnold; Suter, Paolo M (2018). CME: Kardiovaskuläres Screening: Sinn, Unsinn und Bedeutung der Bestimmung von Lipoprotein(a). Praxis, 107(4):215-222.

Abstract

Cardiovascular diseases are still the most important causes for morbidity and mortality in modern society. The im- portance of the early assessment of various cardiovascular risk factors and their control is crucial. Although the international recommendations are gender-specific, the following general recommendation on lipid screening may be formulated: in adults over 35 years, lipid screening should be performed occasionally. If there is an increased cardiovascular risk due to a specific risk constellation, a preventive lipid screening should be carried out already in 20- to 35-year-olds. The cardiovascular risk is calculated using the AGLA score (or other validated scores). Which lipid parameters should be determined for a screening? Ini- tial lipid screening includes total cholesterol, HDL cholesterol, LDL cholesterol (directly measured or calculated), and triglycer- ides (ideally fasted). A recurring question is whether lipoprotein (a), Lp(a), should be measured and what the significance and consequences of elevated values are. In this CME, the present knowledge as well as recommendations about measurement, interpretation as well as therapy options of Lp(a) for the practicing physician are critically discussed. Keywords: Lipoprotein(a), Lp(a), cardiovascular risk, lipid screening, dyslipidemia

Abstract

Cardiovascular diseases are still the most important causes for morbidity and mortality in modern society. The im- portance of the early assessment of various cardiovascular risk factors and their control is crucial. Although the international recommendations are gender-specific, the following general recommendation on lipid screening may be formulated: in adults over 35 years, lipid screening should be performed occasionally. If there is an increased cardiovascular risk due to a specific risk constellation, a preventive lipid screening should be carried out already in 20- to 35-year-olds. The cardiovascular risk is calculated using the AGLA score (or other validated scores). Which lipid parameters should be determined for a screening? Ini- tial lipid screening includes total cholesterol, HDL cholesterol, LDL cholesterol (directly measured or calculated), and triglycer- ides (ideally fasted). A recurring question is whether lipoprotein (a), Lp(a), should be measured and what the significance and consequences of elevated values are. In this CME, the present knowledge as well as recommendations about measurement, interpretation as well as therapy options of Lp(a) for the practicing physician are critically discussed. Keywords: Lipoprotein(a), Lp(a), cardiovascular risk, lipid screening, dyslipidemia

Statistics

Citations

Dimensions.ai Metrics

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic and Policlinic for Internal Medicine
04 Faculty of Medicine > University Hospital Zurich > Institute of Clinical Chemistry
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:General Medicine
Language:German
Date:2018
Deposited On:12 Jul 2018 10:03
Last Modified:24 Sep 2019 23:32
Publisher:Hogrefe Verlag
ISSN:1661-8157
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1024/1661-8157/a002892
PubMed ID:29439638

Download

Full text not available from this repository.
View at publisher

Get full-text in a library