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Modernes Management von Hypophysenadenomen – gegenwärtiger Stand in Diagnostik, Therapie und Nachsorge


Maldaner, Nicolai; Serra, Carlo; Tschopp, Oliver; Schmid, Christoph; Bozinov, Oliver; Regli, Luca (2018). Modernes Management von Hypophysenadenomen – gegenwärtiger Stand in Diagnostik, Therapie und Nachsorge. Praxis, 107(15):825-835.

Abstract

Modern Management of Pituitary Adenomas - Current State of Diagnosis, Treatment and Follow-Up Abstract. Pituitary adenomas (PA) are benign neoplasms originating from parenchymal cells of the anterior pituitary. Tumor mass effect can cause headaches, visual deficits by compression of the optic chiasm, and partial or complete hypopituitarism. Hormone secreting PA can cause several forms of specific syndromes such as Cushing's disease or acromegaly depending on the type of hormone. Endoscopic transsphenoidal resection is the preferred treatment option for most symptomatic or growing PA. Nowadays techniques like high definition intraoperative MRI can assist the surgeon in his goal of maximal safe resection. An exception are prolactinomas which can usually be treated medically with dopamine agonists. Therapy of PA is complex and should be managed in a high-volume center with an interdisciplinary team approach including neurosurgeons and endocrinologists.

Abstract

Modern Management of Pituitary Adenomas - Current State of Diagnosis, Treatment and Follow-Up Abstract. Pituitary adenomas (PA) are benign neoplasms originating from parenchymal cells of the anterior pituitary. Tumor mass effect can cause headaches, visual deficits by compression of the optic chiasm, and partial or complete hypopituitarism. Hormone secreting PA can cause several forms of specific syndromes such as Cushing's disease or acromegaly depending on the type of hormone. Endoscopic transsphenoidal resection is the preferred treatment option for most symptomatic or growing PA. Nowadays techniques like high definition intraoperative MRI can assist the surgeon in his goal of maximal safe resection. An exception are prolactinomas which can usually be treated medically with dopamine agonists. Therapy of PA is complex and should be managed in a high-volume center with an interdisciplinary team approach including neurosurgeons and endocrinologists.

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Additional indexing

Other titles:Modern management of pituitary adenomas - current state of diagnosis, treatment and follow-up
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurosurgery
04 Faculty of Medicine > University Hospital Zurich > Clinic for Endocrinology and Diabetology
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Hypophysenadenom, Sellatumor, Prolaktinom, Hypophyseninsuffizienz, endoskopische transsphenoidale Chirurgie
Language:English
Date:July 2018
Deposited On:24 Aug 2018 16:43
Last Modified:17 Sep 2019 19:25
Publisher:Hogrefe Verlag
ISSN:1661-8157
OA Status:Closed
Publisher DOI:https://doi.org/10.1024/1661-8157/a003035
PubMed ID:30043702

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