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Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study


Salazar-Vizcaya, Luisa; Wandeler, Gilles; Fehr, Jan; Braun, Dominique; Cavassini, Matthias; Stoeckle, Marcel; Bernasconi, Enos; Hoffmann, Matthias; Rougemont, Mathieu; Béguelin, Charles; Rauch, Andri; Swiss HIV Cohort Study (2018). Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study. Open Forum Infectious Diseases, 5(7):ofy154.

Abstract

In the Swiss HIV Cohort Study, the number of people who inject drugs with replicating hepatitis C virus (HCV) infection decreased substantially after the introduction of direct-acting antivirals (DAAs). Among men who have sex with men, the increase in DAA uptake and efficacy was counterbalanced by frequent incident HCV infections.

Abstract

In the Swiss HIV Cohort Study, the number of people who inject drugs with replicating hepatitis C virus (HCV) infection decreased substantially after the introduction of direct-acting antivirals (DAAs). Among men who have sex with men, the increase in DAA uptake and efficacy was counterbalanced by frequent incident HCV infections.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:July 2018
Deposited On:05 Sep 2018 15:34
Last Modified:24 Sep 2019 23:35
Publisher:Oxford University Press
ISSN:2328-8957
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/ofid/ofy154
PubMed ID:30027103

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