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Cost estimates for HIV care and patient characteristics for health resource utilisation from linkage of claims data with the Swiss HIV Cohort Study


Leon-Reyes, Selene; Schäfer, Juliane; Früh, Mathias; Schwenkglenks, Matthias; Reich, Oliver; Schmidlin, Kurt; Staehelin, Cornelia; Battegay, Manuel; Cavassini, Matthias; Hasse, Barbara; Bernasconi, Enos; Calmy, Alexandra; Hoffmann, Matthias; Schoeni-Affolter, Franziska; Zhao, Hongwei; Bucher, Heiner C (2019). Cost estimates for HIV care and patient characteristics for health resource utilisation from linkage of claims data with the Swiss HIV Cohort Study. Clinical Infectious Diseases, 68(5):827-833.

Abstract

Background Comprehensive and representative data on resource use is critical for health policy decision making but often lacking for HIV infection. Privacy preserving probabilistic record linkage of claim and cohort study data may overcome these limitations. Methods Encrypted dates of birth, gender, study center and antiretroviral therapy (ART) of the Swiss HIV Cohort Study (SHCS) from 2012 and 2013 were linked by privacy preserving probabilistic record linkage with claim data from the largest health insurer covering 15% of the Swiss residential population. We modeled predictors for mean annual costs adjusting for censoring and grouped patients by cluster analysis into 3 risk groups for resource use. Results The matched subsample of 1196 patients from 9326 SHCS and 2355 claim records was representative for all SHCS patients on ART. Corrected mean total cost (SE) in 2012 and 2013 were USD 30'462 (582) and USD 30'965 (629) and mainly accrued in ambulatory care for ART (70% of mean costs). The low risk group for resource use had mean annual cost of USD 26'772 (536) and USD 26'132 (589) in 2012 and 2013. In the moderate and high risk groups annual costs for 2012 and 2013 were higher by USD 3'526 [1'907; 5'144] (13%) and 4'327 [2'662; 5'992] (17%) and USD 14'026 [8'763; 19'289 (52%) and 13'567[8'844; 18'288] (52%), respectively. Conclusions In a representative subsample of patients from linkage of SHCS and claim data, ART was the major cost factor but patient profiling allowed to identify factors related to higher resource use.

Abstract

Background Comprehensive and representative data on resource use is critical for health policy decision making but often lacking for HIV infection. Privacy preserving probabilistic record linkage of claim and cohort study data may overcome these limitations. Methods Encrypted dates of birth, gender, study center and antiretroviral therapy (ART) of the Swiss HIV Cohort Study (SHCS) from 2012 and 2013 were linked by privacy preserving probabilistic record linkage with claim data from the largest health insurer covering 15% of the Swiss residential population. We modeled predictors for mean annual costs adjusting for censoring and grouped patients by cluster analysis into 3 risk groups for resource use. Results The matched subsample of 1196 patients from 9326 SHCS and 2355 claim records was representative for all SHCS patients on ART. Corrected mean total cost (SE) in 2012 and 2013 were USD 30'462 (582) and USD 30'965 (629) and mainly accrued in ambulatory care for ART (70% of mean costs). The low risk group for resource use had mean annual cost of USD 26'772 (536) and USD 26'132 (589) in 2012 and 2013. In the moderate and high risk groups annual costs for 2012 and 2013 were higher by USD 3'526 [1'907; 5'144] (13%) and 4'327 [2'662; 5'992] (17%) and USD 14'026 [8'763; 19'289 (52%) and 13'567[8'844; 18'288] (52%), respectively. Conclusions In a representative subsample of patients from linkage of SHCS and claim data, ART was the major cost factor but patient profiling allowed to identify factors related to higher resource use.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:15 February 2019
Deposited On:13 Sep 2018 11:49
Last Modified:16 Feb 2019 02:01
Publisher:Oxford University Press
ISSN:1058-4838
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/cid/ciy564
PubMed ID:30020416

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