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Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition?


Suter, Paolo M; Vetter, Wilhelm (2009). Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition? Nutrition Reviews, 58(10):319-323.

Abstract

Despite modern pharmacologic agents in the therapy of heart failure, the prevalence of heart failure is increasing worldwide. In the vitamin B1 deficiency disease beriberi, cardiac symptoms may represent the central feature. Two new studies confirmed that all diuretics lead to increased uri- nary thiamin excretion depending on the urinary flow rate. In a subject at risk, such as an elderly patient, chronic diuretic treatment may lead to a subclinical thiamin deficiency. Whether subclinical thiamin nutriture is a modulator of the prevalence andlor severity of heart failure is not known; however, it seems to be plausible from the metabolic point of view

Abstract

Despite modern pharmacologic agents in the therapy of heart failure, the prevalence of heart failure is increasing worldwide. In the vitamin B1 deficiency disease beriberi, cardiac symptoms may represent the central feature. Two new studies confirmed that all diuretics lead to increased uri- nary thiamin excretion depending on the urinary flow rate. In a subject at risk, such as an elderly patient, chronic diuretic treatment may lead to a subclinical thiamin deficiency. Whether subclinical thiamin nutriture is a modulator of the prevalence andlor severity of heart failure is not known; however, it seems to be plausible from the metabolic point of view

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:Unspecified
Scopus Subject Areas:Health Sciences > Medicine (miscellaneous)
Health Sciences > Nutrition and Dietetics
Language:English
Date:27 April 2009
Deposited On:09 Oct 2018 14:28
Last Modified:15 Apr 2021 14:47
Publisher:Oxford University Press
ISSN:0029-6643
OA Status:Green
Publisher DOI:https://doi.org/10.1111/j.1753-4887.2000.tb01827.x
PubMed ID:11127971

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