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Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex


Breymann, Christian; von Seefried, Bettina; Stahel, Michele; Geisser, Peter; Canclini, Camillo (2007). Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex. Journal of Perinatal Medicine, 35(2):115-118.

Abstract

Objective: To study the transfer of parenteral iron sucrose into maternal milk in the postpartum period. Study design: Ten healthy lactating mothers with functional iron deficiency 2-3days after delivery received 100mg intravenous iron sucrose and were observed together with a control group (n=5) without iron treatment during four days. Milk samples were taken before the treatment and every day afterwards. Results: Mean milk iron levels at baseline were 0.43 and 0.46mg/kg in the treatment and control group and decreased until the end of observation in both groups by 0.11mg/kg. No significant difference between the groups was found on any study day as well as in the mean change from baseline over all four days. Conclusion: We could not show transfer of iron-sucorose into maternal milk for the given dosage. Since parenteral iron sucrose is widely used in obstetrics, the results provide information about safety of parenteral iron sucrose in the lactation period. The findings are also in agreement with other reports on active biological mammary gland regulation of milk iron concentration

Abstract

Objective: To study the transfer of parenteral iron sucrose into maternal milk in the postpartum period. Study design: Ten healthy lactating mothers with functional iron deficiency 2-3days after delivery received 100mg intravenous iron sucrose and were observed together with a control group (n=5) without iron treatment during four days. Milk samples were taken before the treatment and every day afterwards. Results: Mean milk iron levels at baseline were 0.43 and 0.46mg/kg in the treatment and control group and decreased until the end of observation in both groups by 0.11mg/kg. No significant difference between the groups was found on any study day as well as in the mean change from baseline over all four days. Conclusion: We could not show transfer of iron-sucorose into maternal milk for the given dosage. Since parenteral iron sucrose is widely used in obstetrics, the results provide information about safety of parenteral iron sucrose in the lactation period. The findings are also in agreement with other reports on active biological mammary gland regulation of milk iron concentration

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Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 January 2007
Deposited On:26 Oct 2018 16:33
Last Modified:24 Sep 2019 23:40
Publisher:De Gruyter
ISSN:0300-5577
OA Status:Green
Publisher DOI:https://doi.org/10.1515/jpm.2007.036
Related URLs:https://www.swissbib.ch/Search/Results?lookfor=nationallicencegruyter101515JPM2007036 (Library Catalogue)

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