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An information-carrying and knowledge-producing molecular machine. A Monte-Carlo simulation


Kuhn, Christoph (2012). An information-carrying and knowledge-producing molecular machine. A Monte-Carlo simulation. Journal of Molecular Modeling, 18(2):607-609.

Abstract

The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as assembler-hairpins-devices and, at a later stage, an assembler-hairpins-enzyme device—a first translation machine

Abstract

The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as assembler-hairpins-devices and, at a later stage, an assembler-hairpins-enzyme device—a first translation machine

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Physical Sciences > Catalysis
Physical Sciences > Computer Science Applications
Physical Sciences > Physical and Theoretical Chemistry
Physical Sciences > Organic Chemistry
Physical Sciences > Computational Theory and Mathematics
Physical Sciences > Inorganic Chemistry
Language:English
Date:1 February 2012
Deposited On:28 Nov 2018 16:05
Last Modified:29 Nov 2023 08:00
Publisher:Springer
ISSN:0948-5023
OA Status:Hybrid
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1007/s00894-011-1081-9
PubMed ID:21559961
  • Content: Published Version
  • Language: English
  • Description: Nationallizenz 142-005