Komminoth, Paul; Heitz, Philipp U; Roth, Jürgen (1999). Human insulinoma: clinical, cellular, and molecular aspects. Endocrine Pathology, 10(4):269-281.
Insulinoma is the most frequently encountered functioning endocrine pancreatic tumor in humans. In this overview we summarize morphological and clinical features of insulinomas, report about the proinsulin-insulin conversion in normal and neoplastic B-cells, discuss the new classification, the criteria of malignancy, and the clonal composition of endocrine pancreatic tumors, and outline recent findings on the molecular pathology of these tumors
Insulinoma is the most frequently encountered functioning endocrine pancreatic tumor in humans. In this overview we summarize morphological and clinical features of insulinomas, report about the proinsulin-insulin conversion in normal and neoplastic B-cells, discuss the new classification, the criteria of malignancy, and the clonal composition of endocrine pancreatic tumors, and outline recent findings on the molecular pathology of these tumors
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | National licences > 142-005 |
| Dewey Decimal Classification: | Unspecified |
| Scopus Subject Areas: | Health Sciences > Pathology and Forensic Medicine
Health Sciences > Endocrinology, Diabetes and Metabolism Life Sciences > Endocrinology |
| Language: | English |
| Date: | 1 December 1999 |
| Deposited On: | 05 Dec 2018 19:23 |
| Last Modified: | 26 Jan 2022 18:12 |
| Publisher: | Springer |
| ISSN: | 1046-3976 |
| OA Status: | Green |
| Publisher DOI: | https://doi.org/10.1007/bf02739769 |
| PubMed ID: | 12114763 |
Komminoth, Paul