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Bmi1 in development and tumorigenesis of the central nervous system


Shakhova, Olga; Leung, Carly; Marino, Silvia (2005). Bmi1 in development and tumorigenesis of the central nervous system. Journal of Molecular Medicine, 83(8):596-600.

Abstract

The role of the Polycomb group gene Bmi1 in proliferation control of lymphoid and neuronal progenitors as well as in self-renewal of haematopoietic and neural stem cells has been recently demonstrated. Here we review these recent findings with particular regard to their implications for central nervous system development and tumorigenesis

Abstract

The role of the Polycomb group gene Bmi1 in proliferation control of lymphoid and neuronal progenitors as well as in self-renewal of haematopoietic and neural stem cells has been recently demonstrated. Here we review these recent findings with particular regard to their implications for central nervous system development and tumorigenesis

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Molecular Medicine
Life Sciences > Drug Discovery
Health Sciences > Genetics (clinical)
Language:English
Date:1 August 2005
Deposited On:23 Oct 2018 16:05
Last Modified:15 Apr 2021 14:53
Publisher:Springer
ISSN:0946-2716
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s00109-005-0682-0

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