Navigation auf zora.uzh.ch

Search ZORA

ZORA (Zurich Open Repository and Archive)

A generalization of the van-der-Pol oscillator underlies active signal amplification in Drosophila hearing

Stoop, R; Kern, A; Göpfert, M C; Smirnov, D A; Dikanev, T V; Bezrucko, B P (2006). A generalization of the van-der-Pol oscillator underlies active signal amplification in Drosophila hearing. European biophysics journal : EBJ, 35(6):511-516.

Abstract

The antennal hearing organs of the fruit fly Drosophila melanogaster boost their sensitivity by an active mechanical process that, analogous to the cochlear amplifier of vertebrates, resides in the motility of mechanosensory cells. This process nonlinearly improves the sensitivity of hearing and occasionally gives rise to self-sustained oscillations in the absence of sound. Time series analysis of self-sustained oscillations now unveils that the underlying dynamical system is well described by a generalization of the van-der-Pol oscillator. From the dynamic equations, the underlying amplification dynamics can explicitly be derived. According to the model, oscillations emerge from a combination of negative damping, which reflects active amplification, and a nonlinear restoring force that dictates the amplitude of the oscillations. Hence, active amplification in fly hearing seems to rely on the negative damping mechanism initially proposed for the cochlear amplifier of vertebrates

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Life Sciences > Biophysics
Language:English
Date:1 August 2006
Deposited On:09 Dec 2018 16:47
Last Modified:19 Oct 2024 01:41
Publisher:Springer
ISSN:0175-7571
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s00249-006-0059-5
PubMed ID:16612585
Download PDF  'A generalization of the van-der-Pol oscillator underlies active signal amplification in Drosophila hearing'.
Preview
  • Content: Published Version
  • Language: English
  • Description: Nationallizenz 142-005

Metadata Export

Statistics

Citations

Dimensions.ai Metrics
20 citations in Web of Science®
20 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

47 downloads since deposited on 09 Dec 2018
4 downloads since 12 months
Detailed statistics

Authors, Affiliations, Collaborations

Similar Publications